Mystery of the Crooked Cell

SKU: S-53
$75.00

ABOUT THIS PRODUCT:


NGSS-aligned with MS-LS1-A & LS3.A.

This simple lab demonstrates detection of the mutation that causes Sickle Cell Anemia. In this simulation, your students will use electrophoresis to separate dyes that represent patient samples and controls.

• Learn about sickle cell anemia and the mutations that cause it
• Introduce the medical biotechnologies of restriction enzyme digestion and electrophoresis
• Perform agarose gel electrophoresis to separate different sized dye molecules
• Load, run, and analyze simulated patient samples and controls to diagnose this condition

DOWNLOAD SAMPLE INSTRUCTIONS
Details

Group Size:

For 10 lab groups


Time Required:

Complete in 45 minutes


Kit Includes:

Instructions, Ready-to-Load QuickStrip™ Dye Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, Disposable Pipets.

All You Need:

DNA Electrophoresis, Micropipettes: 5-50 µl (Optional), & Microwave or Hot Plate


Storage:

Room Temperature Stable. Storage of Ready-to-Load QuickStrip™ samples in the Refrigerator is Recommended


Resources

Quick Guides:

Safety Data Sheets:

Instructional Videos:

Group Size:

For 10 lab groups


Time Required:

Complete in 45 minutes


Kit Includes:

Instructions, Ready-to-Load QuickStrip™ Dye Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, Disposable Pipets.

All You Need:

DNA Electrophoresis, Micropipettes: 5-50 µl (Optional), & Microwave or Hot Plate


Storage:

Room Temperature Stable. Storage of Ready-to-Load QuickStrip™ samples in the Refrigerator is Recommended