Cholesterol Diagnostics with SYBR® Safe

ABOUT THIS PRODUCT:

Elevated blood cholesterol has been established as a serious risk factor for coronary heart disease and stroke which are leading causes of death in the United States. A disease known as familial hypercholesterolemia (FH) causes an increase in blood levels of the "bad" form of cholesterol, known as low density lipoprotein (LDL). In this electrophoresis experiment, a simulated genetic test for hypercholesterolemia is demonstrated in which patients are tested for a DNA polymorphism linked to the FH gene.

•**Includes SYBR® Safe DNA Stain, NOT FlashBlue™ DNA Stain**
• Discover how doctors identify genetic diseases using molecular technologies
• Explore the genetics of familial hypercholesterolemia
• Perform agarose gel electrophoresis to separate differently-sized DNA molecules
• Load, run, analyze, and size control samples and three patient samples to determine whether patients are normal, heterozygous, or homozygous for the FH mutation

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