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Cholesterol Diagnostics with SYBR® Safe

SKU: 118-S
$109.00

ABOUT THIS PRODUCT:


Elevated blood cholesterol has been established as a serious risk factor for coronary heart disease and stroke which are leading causes of death in the United States. A disease known as familial hypercholesterolemia (FH) causes an increase in blood levels of the "bad" form of cholesterol, known as low density lipoprotein (LDL). In this electrophoresis experiment, a simulated genetic test for hypercholesterolemia is demonstrated in which patients are tested for a DNA polymorphism linked to the FH gene.

**Includes SYBR® Safe DNA Stain, NOT FlashBlue™ DNA Stain**
• Discover how doctors identify genetic diseases using molecular technologies
• Explore the genetics of familial hypercholesterolemia
• Perform agarose gel electrophoresis to separate differently-sized DNA molecules
• Load, run, analyze, and size control samples and three patient samples to determine whether patients are normal, heterozygous, or homozygous for the FH mutation

DOWNLOAD SAMPLE INSTRUCTIONS
Details

Group Size:

For 8 Gels


Time Required:

Complete in 45 minutes


Kit Includes:

Instructions, Ready-to-Load QuickStrip™ DNA Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, SYBR® Safe DNA Stain.


All You Need:

DNA Electrophoresis, Micropipettes: 5-50 µl (Optional), White Light Box, & Microwave or Hot Plate.


Storage: 

Room Temperature Stable. Storage of Ready-to-Load QuickStrip™ samples in the Refrigerator is Recommended.

Resources

Instructional Videos:

BioTech Equipment Tips:

Safety Data Sheets:

Quick Guides:

Group Size:

For 8 Gels


Time Required:

Complete in 45 minutes


Kit Includes:

Instructions, Ready-to-Load QuickStrip™ DNA Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, SYBR® Safe DNA Stain.


All You Need:

DNA Electrophoresis, Micropipettes: 5-50 µl (Optional), White Light Box, & Microwave or Hot Plate.


Storage: 

Room Temperature Stable. Storage of Ready-to-Load QuickStrip™ samples in the Refrigerator is Recommended.

Instructional Videos:

BioTech Equipment Tips:

Safety Data Sheets:

Quick Guides: