116 - Sickle Cell Gene Detection (DNA-based)

Sickle Cell Gene Detection (DNA-based)
Cat. #116

Sickle Cell Anemia is a common genetic disease that causes long rods in red blood cells, giving them a ÒsickledÒ appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage. Sickle Cell Anemia is caused by a single point mutation in the hemoglobin gene that results in a faulty protein. In this experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.

Kit includes: instructions, Ready-to-Load™ DNA samples, UltraSpec-Agarose™ powder, practice gel loading solution, electrophoresis buffer, InstaStain® Methylene Blue and Methylene Blue Plus™ stain, calibrated pipet, 100 ml graduated cylinder, microtipped transfer pipettes.
All you need: electrophoresis tank, power supply, variable micropipet and tips, balance and microwave or hot plate.
For 6 Gels
Complete in 60 minutes

Want to learn more? Download a PDF of the instructions or email us with questions.

Secure Ordering

Catalog # Price Quantity

116 $74

For 6 Gels (6 lanes each) with InstaStain® Methylene Blue

116-Q $99

For 12 Gels (6 lanes each) with InstaStain® Ethidium Bromide

116-B $99

DNA Samples Only for 12 Gels using InstaStain® Methylene Blue or 24 gels using InstaStain® Ethidium Bromide

116-C $149

DNA Samples Only for 24 Gels using InstaStain® Methylene Blue or 48 gels using InstaStain® Ethidium Bromide

You may also place an order by phone, fax, email or regular mail:

E D V O T E K® -- The Biotechnology Education Company®
tel 800.338.6835 | fax 301.340.0582 | info@edvotek.com
Post Office Box 341232; Bethesda, MD 20827-1232 USA

116-Q Results